A Mouse Model for Peritoneal Metastases of Colorectal Origin Recapitulates Patient Heterogeneity

June 10, 2020 | Histopathology

Fresh off Laboratory Investigation, Lab.Equipment has sourced this article for your daily Pathology industry news fix:

The peritoneum is a common site of dissemination in patients with colorectal cancer. In order to identify high-risk patients and improve therapeutic strategies, a better understanding of the peritoneal dissemination process and the reasons behind the high heterogeneity that is observed between patients is required. We aimed to create a murine model to further elucidate the process of peritoneal dissemination and to provide an experimental platform for further studies. We developed an in vivo model to assess patterns of peritoneal dissemination of 15 colorectal cancer cell lines... You can read the full article in the Laboratory Investigation Blog.

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