Database Identifies Gene Regulatory Mechanisms in Immune Cells that Facilitate Type 1 Diabetes

April 15, 2020 | Biotechnology

Reading time: 3 minutes

This week, Lab.Equipment has curated a new Biotechnology article published from Genetic Engineering and Biotechnology News (GEN):

Scientists at St. Jude Children’s Research Hospital report the creation of a database that identifies gene-regulatory mechanisms in immune cells that facilitate Type 1 diabetes. Scientists at St. Jude Children’s Research Hospital report the creation of a database that identifies gene-regulatory mechanisms in immune cells that facilitate Type 1 diabetes. The findings “Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes” appear in Nature Immunology.

“The pool of beta cell-specific CD8+ T cells in type 1 diabetes (T1D) sustains an autoreactive potential despite having access to a constant source of antigen. To investigate the long-lived nature... Read the whole article in the GEN Blog.

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