Genetically Edited Cell Lines Enter the Fast Lane

Current studies involving cellular models of disease confront two challenges: recapitulate what happens in the human body, and access longitudinal information. These challenges, which often limit the accuracy and value of cellular models, are being addressed by ExpressCells, a company that has developed a new gene modification technology to expedite the production of custom, knock-in cell lines.

“When disease models use conventional gene reporter systems, researchers can see whether a protein is promoted, activated, or inhibited, but the model may not accurately replicate what actually happens in the human body,” explains ExpressCells CEO Matthew Handel. “Fixing and staining cells to study endogenous protein targets... View the whole article at the Genetic Engineering and Biotechnology News (GEN) Blog.

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