Heart shape indicative of health

April 29, 2023 | Histopathology

Researchers from the Smidt Heart Institute used deep learning and advanced imaging techniques in examining the genetics of the heart structure. Analyzing cardiac MRI images from 38,897 individuals, data underwent computational models for the identification of genetic markers of the heart that are associated with two cardiac conditions, including atrial fibrillation and cardiomyopathy.

Odoo image and text block

Results indicated that individuals with spherical hearts have a 31% chance of developing atrial fibrillation and 24% more likely to have cardiomyopathy. Looking at the genes linked to sphericity, four genes were identified to be associated with cardiomyopathy: PLN, ANGPT1, PDZRN3, and HLA DR/D - the first three contributing to a greater risk.

Cardiologists stated that one’s heart undergoes changes over the years, becoming rounder over time especially after an individual experienced a major cardiac event like heart attack. Thus, changes in heart shape are initial signs of a disease.

Working with reliable and intuitive imaging that offers comprehensive cardiac measures is crucial in the effective diagnosis and prevention of two life-altering diseases and possibly other medical conditions. Further studies are needed and large biobanks with ample cardiac imaging data provides opportunities for the analysis and definition of variations in cardiac structures and function.

Back To Top
We are fully compliant with the GDPR laws. We promise to safeguard your data and protect your privacy rights.