Identification of Lacrimal Gland Postganglionic Innervation and its Regulation of Tear Secretion

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Tear fluid secreted from the exocrine lacrimal gland (LG) has an essential role in maintaining a homeostatic environment for a healthy ocular surface. It is known that tear secretion is regulated by both the sympathetic and parasympathetic components of the autonomic nervous system, although the contribution of each component is not fully understood. Here, to investigate LG innervation, we identified sympathetic and parasympathetic postganglionic nerves, specifically innervating the mouse LG, by injecting a retrograde neuronal tracer into the LG.... More of this in the The American Journal of Pathology Blog.

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