Implication of Cell Migration Inducing Hyaluronidase 1 (CEMIP) in Hyaluronan Degradation by Synovial Fibroblasts in Patients with Knee Osteoarthritis

Fresh from The American Journal of Pathology, here is a new Pathology article for you:

Cell migration inducing hyaluronidase 1 (CEMIP), also known as hyaluronan (HA)-binding protein involved in HA depolymerization (HYBID), plays a role in HA degradation. Cell migration inducing hyaluronidase 2 (CEMIP2), also known as transmembrane protein 2 (TMEM2), possessing a sequence similarity with HYBID, is reported as a hyaluronidase in mice. However, the expression of these molecules in osteoarthritic synovium and their involvement in HA degradation in synovial fluid (SF) from patients with knee osteoarthritis remain elusive.... Read the full article at the The American Journal of Pathology Blog.

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