Improving Plasmid and Viral Vectors in Cell and Gene Therapy

Cell and gene therapies are redefining the treatments of rare diseases and cancers. Two CAR-T therapies, for instance, rapidly achieved FDA approval in the US and have emerged recently as the new pillars in the treatment of B-cell leukemia. This is a landmark moment for the biopharma industry, with CAR-T therapies expected to dominate the market over the next several years. Yet, despite their meteoric growth, there are several hurdles to overcome when developing efficacious cell and gene therapies, particularly when it comes to the manufacturing of viral vectors—a significant bottleneck in the overall produc... More of this in the GEN Blog.

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