Molecular Profiling of Vascular Remodeling in Chronic Pulmonary Disease

April 17, 2020 | Histopathology

For your weekly Pathology news, Lab.Equipment has curated this notable article from The American Journal of Pathology for you:

Pulmonary Hypertension (PH) and pulmonary vascular remodeling (PVR) are common in a variety of lung diseases leading to right ventricular dysfunction and death. Differences in PVR result in significant prognostic divergences, such as the pulmonary arterial compartment as in pulmonary arterial hypertension (PAH) as well as the venous compartment, as in pulmonary veno-occlusive disease (PVOD). We aimed to identify compartment-specific molecular hallmarks of PVR, considering the risk of life-threatening pulmonary edema in PVOD, if treated by conventional PH-therapy... Read the whole article at the The American Journal of Pathology Blog.

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