Mouse Models of Heart Failure with Preserved or Reduced Ejection Fraction

May 07, 2020 | Histopathology

No need to search at great lengths for the newest Histopathology industry news as Lab.Equipment ensures you’re updated whenever and wherever. This week’s article is freshly curated from The American Journal of Pathology:

Heart failure (HF) is a chronic, complex condition with increasing incidence worldwide, necessitating the development of novel therapeutic strategies. This has led to the current clinical strategies, which only treat symptoms of HF without addressing the underlying causes. Multiple animal models have been developed in an attempt to recreate the chronic HF phenotype that arises following a variety of myocardial injuries. While significant strides have been made in HF research, an understanding of more specific mechanisms will require distinguishing models that resemble HF with preserved ejection fraction (HFpEF) from those with reduced ejection fraction (HFrEF).... Read more at the The American Journal of Pathology Blog.

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