Novel Technique for Producing Retinal Cells May Help in Treating Blindness Among the Elderly

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Genetic Engineering and Biotechnology News (GEN) published an interesting article covering Bio Tech:

Scientists at the Karolinska Institutet and St. Erik Eye Hospital in Sweden say have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. Using the CRISPR/Cas9 gene editing, they have also managed to modify the cells so that they can hide from the immune system to prevent rejection. One study, “Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells,” is published in Nature Communications and the other, “Generation of Retinal Pigment Epithelial Cells Derived from Human Embryonic Stem Cells Lacking Human Leukocyte Antigen Class I and II” in Stem Cell Reports.

Age-related macular degeneration of the eye is the most common cause of blindness in the elderly. This loss of vision is caused by the death of the photoreceptors (the rods and cones) resulting from the degeneration and death o... Want to read more? Visit the GEN​ Blog.

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