Platelet C-type Lectin-like Receptor Reduces Cholestatic Liver Injury in Mice
June 02, 2020 | Histopathology
For the latest news in the Histopath industry, you can always rely on Lab.Equipment as we publish articles from trusted online sources on a day-to-day basis. Here is a noteworthy entry acquired from The American Journal of Pathology:
Cholestatic liver injury leads to liver dysfunction. The available evidence suggests that platelets can either promote or reduce liver injury and fibrosis. We focused on the functions of the c-type lectin-like receptor (CLEC-2), a new special platelet receptor that binds with podoplanin activating platelets. We investigated the role of CLEC-2 and podoplanin in cholestatic liver injury. We injected mice intraperitoneally with weekly doses of anti-CLEC-2 antibody (2A2B10) to achieve effective CLEC-2 inhibition in their platelets... Want to read more? Visit The American Journal of Pathology Blog.
Working in the Histopathology industry and in need of reliable Histopathology lab equipment for your workroom? Go through Lab.Equipment’s selection of Pathology equipment manufactured by globally recognized brands like:
Go for user-friendly Pathology lab equipment for several pathological tests such as:
Dealing with other industrial or scientific applications? No worries. We have you covered. Go though our range of robust lab equipment for pharmaceutical, veterinary, food testing applications and more.