Progressive muscle disorder in mice can be corrected by genetic therapy
May 25, 2023 | Histopathology
Recently, a research team from the Massachusetts General Hospital utilized targeted drugs in restoring muscle strength and correcting myotonia in mice with myotonic dystrophy. These could lead to new treatment approaches for affected patients.
This research study was able to show that muscle fiber type transitions in myotonic dystrophy resulting from myotonia are not irreversible. Clcn1-targeting therapies can be a way to reduce muscle injury in patients.