Pulmonary Eosinophilic Granulomatosis with Polyangiitis has IgG4 Plasma Cells and Immunoregulatory Features

There is no need to search at great lengths for current Pathology industry news as Lab.Equipment guarantees you are updated whenever and wherever. This week’s curated article is fresh from The American Journal of Pathology:

The immunologic mechanisms in eosinophilic granulomatosis with polyangiitis (EGPA) are poorly understood. To characterize pulmonary EGPA’s mechanisms, we examined EGPA paraffin-embedded lung biopsies by immunostaining, RNA sequencing, and reverse transcriptase PCR, compared to normal lung. Novel type 2 findings in EGPA are basophils and increased mast cell contents. There is increased immunostaining for TNF superfamily member 14, confirmed by RNA sequencing. Mast cell degranulation is very sparse.... Want to read more? Visit the The American Journal of Pathology​ Blog.

Supervising Histopath applications like specimen collection and scouting for premium Pathology equipment for your lab? Trust Lab.Equipment for a collection of lab products from recognized brands including Accuris and Radwag. Find lab centrifuges, pipettes, precision scales, and more for differenthistopathology tests here.

Dealing with other applications? No need to worry. We got you covered. Explore our selection of robust lab equipment for pharmaceutical, veterinary, cannabis applications and more.