Sweet and Sticky: Selective Recruitment of Monocyte Subsets by Endothelial N-glycans

Handpicked by Lab.Equipment from The American Journal of Pathology, here is an interesting Histopath industry news for you:

Monocyte rolling, adhesion, and transmigration across the endothelium is mediated by specific interactions between surface adhesion molecules. This process is fundamental to innate immunity and to inflammatory disease, including atherosclerosis where monocyte egress into the intimal space is central to formation of fatty plaques. Monocytes are a heterogeneous population of three distinct subsets of cells, all of which play different roles in atherosclerosis progression. However, it is not well understood how interactions between different monocyte subsets and the endothelium are regulated.... Find the entire article at the The American Journal of Pathology Blog.

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