Synthesized Tumor Cells Allow Scientists to Conduct Research More Efficiently

June 15, 2020 | Biotechnology

Reading time: 2-3 minutes

Today’s Lab.Equipment Biotechnology news comes from GEN – Genetic Engineering and Biotechnology News:

Researchers in Japan say they have replicated cancer cells from diseased bladder tissue in dogs, minimizing the use of costly stem cell products. The synthesized tumor cells allow scientists to diagnose cancer and optimize treatment without putting the patient through tiresome rigors of chemotherapy trial and error, the team adds.

The scientists, led by Tatsuya Usui, PhD, DVM, senior assistant professor from the Laboratory of Veterinary Pharmacology at the Tokyo University of Agriculture and Technology, published their findings “Establishment of 2.5D \ culture model using 3D bladder cancer organoid culture” in Scientific Reports.

Organoids are a niche within the field of 3D bioprinting, which includes a growing stable of chemical and biological processes that generate living tissue for use in research and medical procedures. Clinically viable 3D bioprinting is currently limited to simple structures like a small patch of skin, fat, or cartilage, note the researchers. Ultimately the medical community hopes to generate viable replacement organs, eliminating the need for transplant donors.

Usui’s team set out to create a type of organoids without the use of cell-stimulating supplements and Matrigel, a costly product derived from stem cells harvested from genetically engineered rodents. The scarcity of 3D bioprinting products makes them a poor choice for research on a scale that would yield timely cancer diagnoses and new treatments... You can view the full article in the Genetic Engineering and Biotechnology News (GEN) Blog.

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