The Pathobiology of Skin Ageing: New Insights into an Old Dilemma

April 21, 2020 | Histopathology

There is no need to search high and low for current Histopathology industry news as Lab.Equipment ensures you are updated wherever and whenever. This week’s article comes from The American Journal of Pathology:

Long considered both physiologic and inevitable, skin ageing is a degenerative phenomenon whereby both intrinsic and environmental factors conspire to produce an authentic disease. The consequences of this disorder are many and varied, ranging from atrophy and fragility to defective repair to deficient immunity and vulnerability to certain infections. The pathobiologic basis for skin ageing remains poorly understood. At a cellular level, stem cell dysfunction and attrition appear to be key events, and both genetic and epigenetic factors are involved in a complex interplay that over time results in deterioration of our main protective interface with the external environment.... Find the entire article at the The American Journal of Pathology Blog.

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