A New Lease on Life for shRNA

April 21, 2020 | Biotechnology

Reading time: 6 minutes

For your weekly Biotech news, Lab.Equipment has handpicked this interesting article from GEN for you:

RNA-based therapies are enjoying a renaissance, owing in part to the recent approvals of Alnylam Pharmaceuticals’ RNA interference (RNAi) drugs, Onpattro® (patisiran) and Givlaari (givosiran). RNA-based drugs are also gaining traction because their use to silence gene translation does not involve editing DNA. Such drugs have been approved before for use in the clinic, particularly for the treatment of patients infected with human immunodeficiency virus (HIV). Although many different approaches exist for making use of RNA for therapy, this tutorial will focus on short hairpin RNA (shRNA), an artificial RNA molecule with a tight hairpin turn, and its potential use in developing chimeric antigen... Find the entire article at the GEN Blog.

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