Biology Industry News

In the tumor microenvironment, local immune dysregulation is driven in part by macrophages and dendritic cells that are polarized to a mixed proinflammatory/immune-suppressive phenotype. The unfolded protein...

Unc-51-like autophagy activating kinase 1 (ULK1)–autophagy-related 13 (ATG13) is the most upstream autophagy initiation complex that is phosphorylated by mammalian target-of-rapamycin complex...

Autophagy is an intracellular degradation pathway targeting organelles and macromolecules, thereby regulating various cellular functions. Phosphorylation is a key posttranscriptional protein modification...

Autophagy is the process by which cells degrade and recycle their own components. It helps maintain homeostasis which is crucial to proper cell functioning. Among the different subtypes of autophagy...

Around 194 million birds and 29 million mammals are thought to be killed each year on European roads, according to a new study that has ranked the most vulnerable species.An international research...

nherited prion diseases are caused by autosomal dominant coding mutations in the human prion protein (PrP) gene (PRNP) and account for about 15% of human prion disease cases worldwide. The proposed mechanism...

Inside our cells, DNA is tightly packed and spooled around proteins called histones. Packaging DNA in this way allows large amounts of genetic material to exist inside the cell in a final form called...

There is a broad range of mechanisms associated with chemoresistance, many of which to date are only poorly understood. The so-called cellular stress response—a set of genetic programs that enable...

In breeding programs aimed at conserving animals from small or isolated populations, scientists must balance the competing needs of adding genetic diversity and avoiding the introduction of harmful...

Molecular dynamics simulations (MD) have become a ubiquitous tool in modern life sciences. In these simulations, the interactions between atoms and molecules and their resulting spatial movements are iteratively...

Stenotrophomonas maltophilia are increasingly recognized as significant opportunistic pathogens in healthcare settings worldwide, the global spread of multidrug-resistant strains of this species...

Lab.Equipment has your back when it comes to your everyday Bio industry news fix. Check out today's article that first appeared on Public Library of Science Biology: by Salim T. Islam, Israel Vergara Alvarez, Fares Saïdi, Annick Giuseppi, Evgeny Vinogradov, Gaurav Sharma, Leon Espinosa, Castrese Morrone, Gael Brasseur, Jean-François Guillemot,...

Mitochondrial metabolic remodeling is a hallmark of the Trypanosoma brucei digenetic life cycle because the insect stage utilizes a cost-effective oxidative phosphorylation (OxPhos) to generate ATP...

A new method for engineering living materials called 'MeniFluidics', made by researchers at the University of Warwick could see a transformation in tissue engineering and bio-art, as...

Protected areas across the globe are effectively keeping invasive animals at bay, but the large majority of them are at risk of invasions, finds a China-UK research...

Cerebral cavernous malformations (CCMs) are vascular lesions predominantly developing in the central nervous system (CNS), with no effective treatments other than surgery. Loss-of-function mutation in CCM1/krev...

A type of plant grafting that requires a tremendous amount of precision and skill has now been made faster and easier thanks to a simple transparent container. Researchers at Nagoya University have developed...

For a sperm to fertilize an egg, the sperm must first mature in a man's epididymis. Now, an international team of researchers has identified a chain of events in which a protein secreted...

A group of scientists from CECAD has found a mechanism by which neurodevelopmental diseases concerning neurons can be explained. The loss of a certain enzyme, UBE2K, impedes the differentiation of stem...

Why does poor-quality sleep lead to atherosclerosis? In a diverse sample of over 1,600 individuals, we describe a pathway wherein sleep fragmentation raises inflammatory-related white blood cell counts...