Clinical Trial Evaluating Oral Drug against Coronavirus Expected to Start Later This Spring

April 27, 2020 | Biotechnology

Reading time: 6 minutes

Lab.Equipment has sourced a new article from the Biotechnology industry for you. This one is published by GEN – Genetic Engineering and Biotechnology News:

Clinical studies evaluating an antiviral drug that is in development against SARS-CoV-2 are expected to begin later this spring. Scientists working to develop the drug, which is called EIDD-2801, suggest that if trials are successful, the drug could not only be used to limit the spread of SARS-CoV-2, but could also control future outbreaks of other emerging coronaviruses. EIDD-2801 is an orally available form of the antiviral compound EIDD-1931, which has shown promise in reducing lung damage in animal models.

Researchers at the University of North Carolina (UNC) at Chapel Hill Gillings School of Global Public Health are playing a key role in the development and testing of EIDD-2801. The team, together with U.S. collaborators, has now reported on results from tests evaluating the drug in cultured human lung cells infected with SARS-CoV-2, as well as in mice infected with the related coronaviruses SARS-CoV (severe acute respiratory syndrome-coronavirus) and MERS-CoV (Middle East respiratory syndrome coronavirus). Their results showed that, when used prophylactically, or admi... Read the whole article at the GEN – Genetic Engineering and Biotechnology News Blog.

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