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Fresh from GEN – Genetic Engineering and Biotechnology News, here is a noteworthy Biotech article for you:
The Coalition for Epidemic Preparedness Innovations (CEPI) called for a $2BN fund to be set up to support SARS-CoV-2 vaccine development and global manufacturing capacity expansion in March1. As part of the plan, the organization is mapping capacity and building a facility database to understand what exists globally.
A CEPI spokesperson said, “We are looking for additional facilities to duplicate manufacturing processes in multiple countries to distribute supply around the world. We have a database of more than 200 biological manufacturing organizations and/or fill/finish organizations that we have created for this potential need. A significant number of these already have licensed products or are approved through the World Health Organization (WHO) pre-qualification, which improves the probability of success and supports global distribution.”
But even with existing capacity we will require new plants. “If we need to manufacture billions of doses there will have to be additional manufacturing capacity,” added the spokesperson.
The idea is to establish a reactive network of facilities able to make vaccine when needed. Operating the network requires careful planning, according to CEPI.
“This is a 100-year event and preparing for such is challenging. Capacity could go largely unused for many years and, if it is not used routinely, it is not really ready to respond rapidly. If it is kept busy with other products, it is not available for an outbreak response,” continued the CEPI official. “It is a challenging situation to truly prepare for, but this pandemic will be a strong and lasting memory for all of us and this memory will hopefully support greater investment and diligence in the future.”
Single-use supply chains
CEPI has selected plants based on their manufacturing capacity and flexibility.
“Single-use technologies will be widely used in our response,” pointed out the spokesperson. “T... Read the complete article at the Genetic Engineering and Biotechnology News (GEN) Blog.
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